Ikko

Ikko may refer to:

  • Ikkō-shū, a Buddhist sect
  • Ikkō-ikki, mobs who rose up against samurai rule in 15th and 16th century Japan
  • People

  • Ikko (makeup artist) (born 1962), Japanese makeup artist and TV personality
  • Ikkō Narahara (born 1931), photographer
  • Ikko Tanaka (1930–2002), Japanese graphic designer
  • IKK2

    IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene.

    Function

    IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. IKK's activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF-κB. Activated IKK-β phosphorylates a protein called the inhibitor of NF-κB, IκB (IκBα), which binds NF-κB to inhibit its function. Phosphorylated IκB is degraded via the ubiquitination pathway, freeing NF-κB, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses.

    Clinical significance

    IKK-β plays a significant role in brain cells following a stroke. If NF-κB activation by IKK-β is blocked, damaged cells within the brain stay alive, and according to a study performed by the University of Heidelberg and the University of Ulm, the cells even appear to make some recovery.

    Podcasts:

    PLAYLIST TIME:

    My World

    by: O.C.

    Uh, yeah y'know, shit is wild he, heh
    Can't complain though I'm alive
    Healthy and all a that knahmsayin?
    Just tryin' to do my thang, praise to all
    Bust it that nigga Slick Rick said, I waited long time sweatin' it
    I got jerked but now I'm gettin' it, hazy like asthma bizarre disaster
    Stress almost held me down from bein' a master
    The faster preacher, poet, a teacher, it's been so long like Monifah
    Believe that I'm needed, in rappin', I breathe this
    Some pick up a microphone and can't even achieve this
    Oscar award winning your shit, I'm bored with it
    Stop copy-catting son
    (Why?)
    'Cause your dog did it
    Get your own lingo, make up your own jingle
    Ten years later you be bitin' my single
    Primo, take it downtown, swing it
    Intervenin' on the board, sensimil steamin', yeah
    Catch the vibe like a tribal dance
    In the clubs on the low with the boy stance
    Money rubbin' with a shorty got bumped by a chump
    Tell him, step off, I'm doin' the hump, yeah
    I say it's my world and I won't stop
    And if you stand in my way you bound to get dropped
    Some wish that I was gone 'cause they know I'ma win
    In a minute, I'll be makin' six G's times ten
    I'm the computer, printin' out data take notes
    Then analyze the information and press send
    Freaky like porno, Ron Jeremy saw no
    Obstacle or pussy to stop him from bonin' a hoe
    Me and the mic double trouble
    Chicks look at us like twins, all lovable and huggable
    Prognosis, on the, mic I choke out
    Had the same effects from coughin', blowin' smoke out
    Architect, rap technician, man listen
    It's no doubt you gonna pump this in your system
    My skills ill and all of that above
    Confidence, I'm not worried 'bout a street buzz
    I'm O.C., who you? I never heard of ya
    Get out my face 'fore I turn into a motherfuckin' murderer
    I want the green like indo, a mansion, a car
    A wife who's never been a bimbo
    Too much to ask, well, to me that's simple
    Wanna retire on a yacht called the S. S. Minnow
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    Top choice, this here nigga got poise
    Ain't a man alive who could stop my noise
    I snatch a star from the sky, spark up your lye
    You stand astounded wonderin' how I did it
    Now you're star struck, like I truck gold
    Treatin' me like a nigga havin' a million records sold
    Now a star child, phenomenon like the X-Files
    Rappers know I'm comin' so they go in exile
    Czar in this rap shit, comin' on your mattress
    Microphone fiend, I make beats do back flips
    Fear me like genocide, serious
    How I do it through your stereo, mysterious
    O.C. do demolition, nil competition
    Like robot Kong on a destroy mission
    A matter of life and death you try to fight for breath
    I snatch your heart from a slice through your chest
    Who the best from New York to Bogota?
    Who got face thinkin' they scare me with a scar, shit?
    What I be bringin' is a terrible sight
    A performance never again performed on the mic
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped
    I say it's my world and I won't stop
    And if you stand in my way, you bound to get dropped




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